Links to Alpha-1 Antitrysin Deficiency related clinical trials that are planned, have been completed, or are underway in or have relevance to those affected by AATD in Australia.
Study of INBRX-101 Compared to Plasma-derived A1PI Therapy in Adults With AATD Emphysema (ELEVAATE)
By Inhibrx, Inc.
A Phase 1 Research Study to Evaluate Safety, Tolerability, and Pharmacokinetics of WVE-006 in Healthy Participants With Wild-type AAT Expression (RestorAATion-1) (RestorAATion-1)
By Wave Life Sciences Ltd
A Study to Evaluate the Safety and Efficacy of BEAM-302 in Adult Patients With Alpha-1 Antitrypsin Deficiency (AATD)
By Beam Therapeutics Inc
Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein
By Takeda
Now Closed
A Study of Belcesiran in Patients With A1ATD-Associated Liver Disease (ESTRELLA)
By Dicerna Pharmaceuticals, Inc
Now Closed
By Arrowhead Research Corporation
Now Closed
Zemaira in Subjects With Emphysema Due to Alpha1-Proteinase Inhibitor (API) Deficiency
By CSL Behring
Now Closed
Pharmacokinetic Study of Aralast (Human Alpha1- PI)
By Baxter Healthcare Corporation